Each kidney has an adrenal gland located
above it. The adrenal gland is divided into an inner medulla and
an outer cortex. The medulla synthesizes
amine hormones, the cortex secretes steroid hormones. The
adrenal medulla consists of modified neurons
that secrete two hormones: epinephrine and norepinephrine.
Stimulation of the cortex by the sympathetic
nervous system causes release of hormones into the blood to
initiate the "fight or flight" response.
The adrenal cortex produces several steroid hormones in three
classes: mineralocorticoids, glucocorticoids,
and sex hormones. Mineralocorticoids maintain electrolyte
balance. Glucocorticoids produce a long-term,
slow response to stress by raising blood glucose levels
through the breakdown of fats and proteins;
they also suppress the immune response and inhibit the
inflammatory response.